Dr. Amanda Burmeister earned her B.S. in biology and her Ph.D. in molecular, cellular and developmental biology, both from the University of North Carolina at Charlotte. During her graduate work, she studied the innate immune responses of resident brain cells, specifically microglia and astrocytes, with a focus on investigating endogenously expressed factors that can limit detrimental brain inflammation. To aide in her research, she has laboratory skills that include murine primary glial cell isolation and cell culture, flow cytometry and confocal microscopy, among others. In 2019, she joined the laboratory of Dr. Lena Brundin at Van Andel Institute as a postdoctoral fellow.
Dr. Burmeister is working to identify infectious agents that could trigger Parkinson’s disease by investigating clinical samples for the presence of potential pathogens and by identifying the production of a-synuclein by resident brain cells following infection.
Ph.D. in molecular, cellular and developmental biology, University of North Carolina at Charlotte (Advisor: Ian Marriott, Ph.D.)
Thesis: Detrimental brain inflammation and the role of novel interleukin-10 family members
B.S. in biology, University of North Carolina at Charlotte
UNCC Graduate School Summer Fellowship, Charlotte, NC (June–August 2018)
AAI travel grant, Washington D.C. (May 2017)
AAI travel grant, Seattle, WA (May 2016)
AAI travel grant, New Orleans, LA (May 2015)
To view a list of selected publications click below.
Achtyes E, Keaton SA, Smart L, Burmeister AR, Heilman PL, Krzyzanowski S, Nagalla M, Guillemin GJ, Escobar Galvis ML, Lim CK, Muzik M, Postolache TT, Leach R, Brundin L. 2019. Inflammation and kynurenine pathway dysregulation in post-partum women with severe and suicidal depression. Brain Behav Immun.
Burmeister AR, Johnson MB, Yaemmongkol J, Marriott I. 2019. Murine astrocytes produce IL-24 and are susceptible to the immunosuppressive effects of this cytokine. 16:55.
Burmeister AR, Marriott I. 2018. The Interleukin-10 family of cytokines and their role in the CNS. Frontiers Cell Neuro 12:458.
Burmeister AR, Johnson MB, Chauhan VS, Moerdyk-Schauwecker MJ, Young AD, Cooley ID, Martinez AN, Ramesh G, Philipp MT, Marriott I. 2017. Human microglia and astrocytes constitutively express the neurokinin-1 receptor and functionally respond to substance P. J Neuroinflammation 14(1):245.
Martinez AN, Burmeister AR, Ramesh G, Doyle-Meyers L, Marriott I, Philipp MT. 2017. Aprepitant limits in vivo neuroinflammatory responses in a rhesus model of Lyme neuroborreliosis. J Neuroinflammation 14:37.
Oral presentation American Association of Immunologists conference Washington D.C. (May 2017)
Suppression of glial inflammatory responses by IL-24
Oral presentation American Association of Immunologists conference Seattle, WA (May 2016)
Constitutive and inducible expression of the neurokinin-1 receptor for the inflammatory neuropeptide substance P in human microglia and astrocytes.
Oral presentation American Association of Immunologists conference New Orleans, LA (May 2015)
Astrocytes express novel members of the IL-10 cytokine family in response to bacterial challenge.