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New drug combination targets
aggressive blood cancer

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ORC as Loader of the Rings:
Study details ringed structure of ORC in DNA replication

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Comprehensive study of esophageal cancer reveals several molecular
subtypes, provides new insight into increasingly prevalent disease

New study reveals the structure of DNA
helicase at the replication fork

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Diabetes drug slows experimental Parkinson’s disease progression,
human trials to begin next year

Through biomedical research and science education Van Andel Institute is committed to improving the health and enhancing the lives of current and future generations.

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Hot Papers

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Epigenetic biomarkers for Parkinson’s disease: from diagnostics to therapeutics
Jennifer L. Jakubowski and Viviane Labrie
2017 | Journal of Parkinson’s Disease

Comprehensive characterization, annotation and innovative use of Infinium DNA methylation BeadChip probes
Wanding Zhou, Peter W. Laird, and Hui Shen
2017 | Nucleic Acids Research

Mechanisms of LRRK2-dependent neurodegeneration: role of enzymatic activity and protein aggregation
Md. Shariful Islam and Darren J. Moore
2017 | Biochemical Society Transactions