Through biomedical research and science education Van Andel Institute is committed to improving the health and enhancing the lives of current and future generations.

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Autoinhibition and activation mechanisms of the eukaryotic lipid flippase Drs2p–Cdc50p
Lin Bai, Amanda Kovach, Qinglong You, Hao-Chi Hsu, Gongpu Zhao and Huilin Li
2019 | Nature Communications

Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel
Yihe Huang, Becca Roth, Wei Lü and Juan Du
2019 | eLife

The finger loop of the SRA domain in the E3 ligase UHRF1 is a regulator of ubiquitin targeting and is required for maintaining DNA methylation
Robert M. Vaughan, Scott B. Rothbart and Bradley M. Dickson
In press | Journal of Biological Chemistry