New study reveals the structure of DNA
helicase at the replication fork

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Comprehensive study of esophageal cancer reveals several molecular
subtypes, provides new insight into increasingly prevalent disease

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Diabetes drug slows experimental Parkinson’s disease progression,
human trials to begin next year

Van Andel Research Institute, Cedars-Sinai awarded National Cancer Institute grant for epigenomic data analysis

New computational tool may speed drug discovery

Through biomedical research and science education Van Andel Institute is committed to improving the health and enhancing the lives of current and future generations.

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Hot Papers

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Enhancing the cytotoxic effects of PARP inhibitors with DNA demethylating agents – a potential therapy for cancer
Nidal E. Muvarak, Khadiza Chowdhury, Limin Xia, Carine Robert, Eun Yong Choi, Yi Cai, Marina Bellani, Ying Zou, Zeba N. Singh, Vu H. Duong, Tyler Rutherford, Pratik Nagaria, Søren M. Bentzen, Michael M. Seidman, Maria R. Baer, Rena G. Lapidus, Stephen B. Baylin and Feyruz V. Rassool
2016 | Cancer Cell

Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers
Erik S. Linklater, Elizabeth A. Tovar, Curt J. Essenburg, Lisa Turner, Zachary Madaj, Mary E. Winn, Marianne K. Melnik, Hasan Korkaya, Christiane R. Maroun, James G. Christensen, Matthew R. Steensma, Julie L. Boerner and Carrie R. Graveel
2016 | Oncotarget

A gastric glycoform of MUC5AC is a biomarker of mucinous cysts of the pancreas
Jessica Sinha, Zheng Cao, Jianliang Dai, Huiyuan Tang, Katie Partyka, Galen Hostetter, Diane M. Simeone, Ziding Feng, Peter J. Allen, Randall E. Brand and Brian B. Haab
2016 | PLoS One