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ORC as Loader of the Rings:
Study details ringed structure of ORC in DNA replication

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Comprehensive study of esophageal cancer reveals several molecular
subtypes, provides new insight into increasingly prevalent disease

New study reveals the structure of DNA
helicase at the replication fork

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Diabetes drug slows experimental Parkinson’s disease progression,
human trials to begin next year

Van Andel Research Institute, Cedars-Sinai awarded National Cancer Institute grant for epigenomic data analysis

Through biomedical research and science education Van Andel Institute is committed to improving the health and enhancing the lives of current and future generations.

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Hot Papers

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Structural insights into alternative splicing-mediated desensitization of jasmonate signaling
Feng Zhang, Jiyuan Ke, Li Zhang, Rongzhi Chen, Koichi Sugimoto, Gregg A. Howe, H. Eric Xu, Mingguo Zhou, Sheng Yang He and Karsten Melcher
2017 | Proceedings of the National Academy of Sciences U.S.A.

Transcriptional heterogeneity in the lactase gene within cell-type is linked to the epigenome
Edward Oh, Richie Jeremian, Gabriel Oh, Daniel Groot, Miki Susic, KwangHo Lee, Kelly Foy, Peter W. Laird, Arturas Petronis and Viviane Labrie
2017 | Scientific Reports

The OncoArray Consortium: a network for understanding the genetic architecture of common cancers
Christopher I. Amos…Gerhard A. Coetzee…Douglas F. Easton
2017 | Cancer, Epidemiology, Biomarkers & Prevention