Core leadership and administration

Scott Jewell, Ph.D.
Director, Core Technologies and Services
Director, Pathology and Biorepository Core
Professor, Department of Cell Biology

Dr. Jewell earned his Master’s degree and Ph.D. in experimental pathology and immunology from The Ohio State University. He served at Ohio State as director for the Human Tissue Resource Network and as associate director of the OSU Comprehensive Cancer Center’s Biorepository and Biospecimen Resource, where his dedicated, creative efforts led to the development of a state-of-the-art tissue procurement and biorepository system. He was elected President of the International Society for Biological and Environmental Repositories (ISBER) for 2009–2010 and joined Van Andel Institute in 2010 as a professor and as director of the Core Technologies and Services  and the Pathology and Biorepository Core. He is past a member of the College of American Pathologist’s (CAP) Biorepository Accreditation Program (2010-2018) and presently is on the editorial board of the journal Biopreservation and Biobanking and several cancer center’s external advisory board for biospecimen resources.

Mary Winn, Ph.D.
Manager, Program Evaluation and Coordination

Dr. Winn earned her Ph.D. from the University of California, San Diego and completed a postdoctoral fellowship at Van Andel Institute (VAI) before moving to the position of Bioinformatics and Biostatistics Core manager in 2013. Winn’s research focused, in part, on the translation of genomics to the clinic through the development of diagnostic and prognostic biomarkers of disease. During her tenure, Winn brought together a strong team of scientists dedicated to supporting exceptional science through robust experimental design and analysis. In 2017, she was promoted to Program Evaluation and Coordination Manager, and oversees initiatives involving planning, review and evaluation, funding, education, outreach and community engagement, and communication and marketing across all of VAI’s Core Technologies and Services. She also is an instructor in Van Andel Institute Graduate School, an active member of the Association of Biomolecular Resource Facilities (ABRF), and an ardent supporter of women in science, currently serving as the vice president of the Association of Women in Science West Michigan chapter and as chair of VAI’s Women in Science, Education, Engineering, and Research (WISER) group.

Lori Moon, Executive MBA
Senior Administrative Assistant II

Lori Moon joined Van Andel Institute in 2012 after earning an Executive MBA from Davenport University. She has more than 30 years of experience in high-level administrative support, and manages an array of day-to-day front office responsibilities across the Institute’s Cores, including billing, reporting and CrossLab.

Marie Adams, M.S.
Director, Genomics Core

As manager of VAI’s Genomics Core, Marie Adams is an expert in the latest next-generation sequencing techniques. After earning an M.S. in genetics from Iowa State University, she served as a research assistant in the Division of Hematology/Oncology at Cincinnati Children’s Hospital where she evaluated novel small-molecular inhibitors as potential cancer therapies. She then moved to University of Wisconsin Biotechnology Center as the research lead and next-generation sequencing core manager for the DNA Sequencing Facility. Marie joined VAI in September 2016.

Bryn Eagleson, MLAS, LATG
Director, Vivarium and Transgenics Core

Bryn Eagleson began her career in laboratory animal services in 1981 with Litton Bionetics at the National Cancer Institute’s Frederick Cancer Research and Development Center (NCI-FCRDC) in Maryland. In 1983, she joined the Johnson & Johnson Biotechnology Center in San Diego, California. She returned to the NCI-FCRDC in 1988, where she managed the transgenic mouse colony and continued to develop her skills in transgenic technology. In 1999, Ms. Eagleson joined VAI as the Director of Vivarium and Transgenics where she supports VAI researchers through the management of vivarium and transgenic services. Ms. Eagleson earned a B.S. degree in psychology from the University of Maryland University College and a Master’s degree in Laboratory Animal Science from Drexel University.

Corinne Esquibel, Ph.D.
Manager, Optical Imaging Core

Dr. Corinne Esquibel earned a B.S. in biology from Truman State University followed by a Ph.D. in molecular and cellular pharmacology from University of Wisconsin-Madison, where she studied circuit-level neuroscience using optical imaging methods. She then joined the Laboratory for Optical and Computational Instrumentation (LOCI) at University of Wisconsin as a postdoctoral researcher under the mentorship of Kevin W. Eliceiri. In addition to designing and implementing intravital, in vivo, ex vivo and in vitro imaging studies for a range of research applications, Corinne focused a significant portion of her training on the effective management of microscopy core facilities. In 2017, she joined Van Andel Institute as manager of its Optical Imaging Core, which provides comprehensive imaging services to investigators at the VAI and their collaborators.

Scott A. Givan, Ph.D.
Director, Bioinformatics and Biostatistics Core

Dr. Scott Givan is an informatics expert with more than two decades of experience analyzing, summarizing and visualizing large, multidimensional biological datasets and managing informatics cores and high-performance computing infrastructures.

He earned his Ph.D. in biology from University of Oregon, and subsequently served in a number of informatics management and faculty roles. Prior to joining Van Andel Institute in 2019 as director of its Bioinformatics and Biostatistics Core, he was the associate director of the Informatics Research Core Facility at University of Missouri. While there, he served as co-PI or co-investigator on grants that supported research into GABA receptor expression, anti-human papilloma virus drug-DNA interactions and the genetic relationship between plant morphology and seed amino acid characteristics. He also participated in numerous projects dealing with metagenomics, microbiomics, genome assembly and annotation and transcriptomics.

His work has been published in numerous high-impact journals, including Science, Nature, Genome Biology and Nucleic Acids Research.

Galen Hostetter, M.D.
Associate Core Director, Pathology and Biorepository Core

Dr. Hostetter received his M.D. from the University of Pennsylvania in 1993. He is board certified in pathology and his research throughout the past 15 years has focused on colorectal cancer and spans a range of genomic and protein-based assays for molecular characterization of clinical samples. He was a staff pathologist at TGen from 2003 to 2011 and directed the Tissue Microarray (TMA) service center and pathology services. He supports basic science research through the validation of candidate biomarkers using a range of clinical derived materials, including cell lines, fresh frozen or paraffin tissues. His laboratory also qualified clinical samples for downstream DNA, RNA species and protein applications.

Huilin Li, Ph.D.
Director, Cryo-EM Core

Huilin Li is an internationally recognized structural biologist with more than 20 years of experience in cryo-electron microscopy (cryo-EM). His current work focuses primarily on the structural basis of DNA replication, the bacterial proteasome system and regulation and modification of the Notch receptor.

Dr. Li earned his Ph.D. in electron crystallography from the University of Science and Technology Beijing, where he trained with the late Prof. K.H. Kuo. He then completed postdoctoral research in the labs of Dr. Bing Jap and Dr. Kenneth Downing at Lawrence-Berkeley National Laboratory, where he studied membrane channels and microtubule structure by cryo-EM. From there, he joined Brookhaven National Laboratory as an associate biophysicist, rising through the ranks to attain a tenured position. In 2010, he joined Stony Brook University as a professor in the Department of Biochemistry and Cell Biology while also maintaining a summer appointment at Brookhaven. He is now a professor in Van Andel Institute’s Center for Epigenetics.

Ryan Sheldon, Ph.D.
Manager, Metabolomics and Bioenergetics Core

Ryan Sheldon, Ph.D. earned a B.A. in health/premedical studies and an M.S. in kinesiology from Purdue University before earning a Ph.D. in exercise physiology from University of Missouri. Later, as a postdoctoral fellow in biochemistry at University of Iowa, Dr. Sheldon earned an NIH F32 award to investigate regulation of hepatic lipogenesis by a mitochondrial pyruvate carrier-citrate carrier axis. He also helped develop the analytical capabilities necessary to establish the University of Iowa’s Metabolomics Core. He joined Van Andel Institute in 2019, where he employed his expertise to launch the Institute’s state-of-the-art Metabolomics and Bioenergetics Core, which provides advanced mass spectrometry services for VAI scientists and trainees.

Rachael Sheridan, Ph.D., SCYM(ASCP)
Manager, Flow Cytometry Core

Rachael Sheridan earned her Ph.D. in biochemistry from the University of Wisconsin-Madison and also holds a professional cytometry certification (CCy). She has extensive experience with experimental design, panel design and optimization, high-speed cell sorting, and training of researchers. Prior to joining Van Andel Institute in October 2016, she was an instrumentation specialist in the University of Wisconsin Comprehensive Cancer Center Flow Cytometry Laboratory, which serves more than 600 internal and external scientists.

Gongpu Zhao, Ph.D.
Manager, Cryo-EM Core

Gongpu Zhao, Ph.D., joined Van Andel Institute in 2016 as manager of the Cryo-EM Suite. He came to Grand Rapids from a postdoctoral fellowship in the Peijun Zhang Laboratory at University of Pittsburgh where, in 2013, he was part of the team that uncovered the structure of the HIV-1 virus’s capsid, the outer “shell” of the virus. Prior to joining the Zhang Laboratory, he was a postdoctoral fellow in the labs of Michael Treacy, Ph.D., and Peter Buseck, Ph.D., at Arizona State University. He earned his Ph.D. in physics in Dr. Lu-chang Qin’s lab from University of North Carolina at Chapel Hill.