Scientists in the Institute’s Center for Cancer and Cell Biology investigate the mechanisms that give rise to diseases such as cancer, osteoporosis, osteoarthritis, diabetes and rare disorders such neurofibromatosis type 1 with the goal of developing better diagnostics and treatments.
Bai L, You Q, Feng X, Kovach A, Li H. 2020. Structure of the ER membrane complex, a transmembrane-domain insertase. Nature.
Ruan Z, Orozco IJ, Du J#, Lü W#. 2020. Structures of human Pannexin 1 reveal ion pathways and mechanism of gating. Nature.
Diegel CR, Hann S, Ayturk UM, Hu JCW, Lim K, Droscha CJ, Madaj ZB, Foxa GE, Izaguirre I, VAI Vivarium and Transgenics Core, Paracha N, Pidhaynyy B, Dowd TL, Robling AG, Warman ML, Williams BO. 2020. An osteocalcin-deficient mouse strain without endocrine abnormalities. PLOS Genet.
Izreig S, Gariepy A, Kaymak I, Bridges HR, Donayo AO, Bridon G, DeCamp LM, Kitchen-Goosen SM, Avizonis D, Sheldon RD, Laister R, Minden MD, Johnson NA, Duchaine TF, Rudoltz MS, Yoo S, Pollak MN, Williams KS, Jones RG. 2020. Repression of LKB1 by miR-17~92 sensitizes MYC-dependent lymphoma to biguanide treatment. Cell Rep Med.
Cordeiro B, Jeon P, Boukhaled GM, Carrado M, Lapohos O, Roy DG, Williams KS, Jones RG, Gruenheid S, Sagan SM, Krawczyk CM. 2020.MicroRNA-9 fine-tunes dendritic cell function by suppressing negative regulators in a cell-type-specific manner. Cell Rep 31(4).
March 2, 2020
Mark your calendars for the 2020 Origins of Cancer symposium!
Origins of Cancer is a one-day symposium that brings together students, scientists and medical professionals to discuss the latest breakthroughs in cancer research. This year’s meeting will highlight the tumor macroenvironment, which comprises near and far cells, tissues and systems that interact with primary cancer cells to promote tumor survival. Invited speakers also will discuss novel and integrative treatment approaches that target this larger interactome to outsmart cancer cells.
Open positions in the Center for Cancer and Cell Biology
You can view all of the Institute’s job postings here.
Did you know?
Van Andel Institute Graduate School offers a rigorous, research-intensive Ph.D. program in molecular and cellular biology. Learn more here.