616.234.5000

Yue Ma, Ph.D.

Yue Ma, Ph.D.
Postdoctoral fellow, Ma Laboratory
616.234.5827

Biography

Dr. Yue Ma earned her B.S. in veterinary medicine from Jilin University in China and her Ph.D. in immunology from the Chinese Center for Disease Control and Prevention. Her graduate work focused on neurodegenerative disease and scrapie-infected cultured cells in rodent models. In 2018, she joined the laboratory of Dr. Jiyan Ma at Van Andel Research Institute as a postdoctoral fellow.

 

Current research focus

Dr. Ma investigates immunological approaches, including active and passive immunotherapy, to develop ways to prevent and treat prion disease.

Education & Training

Ph.D. in immunology, Chinese Center for Disease Control and Prevention (Advisor: Dr. Xiao-ping Dong)
Thesis: The relationship between NF-κB signal pathway and prion disease

B.S. in veterinary medicine, Jilin University, Changchun, China

Awards & External Funding

2016 Scholarship of China CDC

2015 Scholarship of Harbin Veterinary Research Institute, CAAS

2009 Scholarship of Jilin University, China

2008 Scholarship of Jilin University, China

Publications

To view a list of selected publications click below.

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Ma Y, Shi Q, Xiao K, Wang J, Chen C, Gao LP, Gao C, Dong XP. 2018. Stimulations of the culture medium of activated microglia and TNF-alpha on scrapie infected cell line decrease the cell viability and induce marked necroptosis that also occurs in the brains from the patients of human prion diseases. ACS Chem Neurosci.

Ma Y, Shi Q, Wang J, Xiao K, Sun J, Lv Y, Guo M, Zhou W, Chen C, Gao C, Zhang BY, Dong XP. 2017. Reduction of NF-κB (p65) in scrapie-infected cultured cells and in the brains of scrapie-infected rodents. ACS Chem Neurosci.

Guo YJ, Shi Q, Yang XD, Li JL, Ma Y, Xiao K, Chen C, Han J, Dong XP. 2017. Increases of Galectin-1 and its S-nitrosylated form in the brain tissues of scrapie-infected rodent models and human prion diseases. Mol Neurobiol 54(5):3707–3716.

Yang X, Shi Q, Sun J, Lv Y, Ma Y, Chen C, Xiao K, Zhou W, Dong XP. 2017. Aberrant Alterations of Mitochondrial Factors Drp1 and Opa1 in the Brains of Scrapie Experiment Rodents. J Mol Neurosci 61(3):368–378.

Chen C, Xu XF, Zhang RQ, Ma Y, Lv Y, Li JL, Shi Q, Xiao K, Sun J, Yang XD, Shi Q, Dong XP. 2017. Remarkable increases of α1-antichymotrypsin in brain tissues of rodents during prion infection. Prion 11(5):338–351.

Zhang RQ, Chen C, Xiao LJ, Sun J, Ma Y, Yang XD, Xu XF, Xiao K, Shi Q, Chen ZB, Dong XP. 2017. Aberrant alterations of the expressions and S-nitrosylation of calmodulin and the downstream factors in the brains of the rodents during scrapie infection. Prion 11(5):352–367.

Ma Y, Liu D, Gao J, Wang X. 2015. Similar regulation of two distinct UL24 promoters by regulatory proteins of equine herpesvirus type 1 (EHV-1). FEBS Lett 589(13):1467–1475.