616.234.5000

Xue Qing (David) Wang, Ph.D.

Xue Qing (David) Wang, Ph.D.
Postdoctoral fellow, Pfeifer Laboratory
616.234.5380

Biography

Dr. Xue Qing (David) Wang earned his B.S. and Ph.D. in biochemistry from McGill University. His graduate work focused on the functional role of long non-coding RNAs and epigenetic changes during cell differentiation, and development of the “carbon-copy chromatin immunoprecipitation sequencing” (or 2C-ChIP) methodology. Along with his research work, he also taught as a graduate assistant at McGill on nucleic acids. In 2018, he joined the laboratory of Dr. Gerd Pfeifer at Van Andel Research Institute as a postdoctoral fellow.

 

Current research focus

Investigating chromatin conformational changes in leukemia

Education & Training

Ph.D. in biochemistry, McGill University (Advisor: Dr. Josée Dostie)
Thesis: Long non-coding RNA, chromatin structure and 3-D chromatin organization: A triumvirate of regulators at the HOXA locus

B.S. in biochemistry, McGill University

Awards & External Funding

Fonds de recherche santé (FRSQ), Doctoral Training award (2013–2016)

Cole Foundation Fellowship (2010–2012)

Publications

To view a list of selected publications click below.

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Wang XQ, Dostie J. 2017. Reciprocal regulation of chromatin state and architecture by HOTAIRM1 contributes to temporal collinear HOXA gene activation. Nucleic Acids Res 45:1091–1104.

Wang XQ, Dostie J. 2016 Chromosome folding and its regulation in health and disease. Curr Opin Genet Dev 43:23-30.
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Dube JC, Wang XQ, Dostie J. 2016. Spatial organization of epigenomes. Curr Mol Biol Rep 2:1–9.

Rousseau M, Ferraiuolo MA, Crutchley JL, Wang XQ, Miura H, Blanchette M, Dostie J. 2014. Classifying leukemia types with chromatin conformation data. Genome Biol 15:R60.

Assadian S, El-Assaad W, Wang XQ, Gannon PO, Barres V, Latour M, Mes-Masson AM, Saad F, Sado Y, Dostie J, Teodoro JG. 2012. p53 inhibits angiogenesis by inducing the production of Arresten. Cancer Res 72(5):1270–1279.

Wang XQ, Crutchley JL, Dostie J. 2011. Shaping the genome with non-coding RNAs. Curr Genomics 12:307–321.

Ferraiuolo MA, Rousseau M, Miyamoto C, Shenker S, Wang XQ, Nadler M, Blanchette M, Dostie J. 2010. The three-dimensional architecture of Hox cluster silencing. Nucleic Acids Res 38:7472–7484.

Crutchley JL, Wang XQ, Ferraiuolo MA, Dostie J. 2010. Chromatin conformation signatures: ideal human disease biomarkers? Biomark Med 4:611–629.