T. K. Martin Tsui, Ph.D.

T. K. Martin Tsui, Ph.D.
Postdoctoral fellow, Du Laboratory


Dr. Martin Tsui earned his Ph.D. in molecular biophysics from Florida State University and his B.S. in chemistry from University of California, San Diego. His graduate work focused on characterizing various CRISPR proteins, including the world first thermophilic Cas9, AceCas9. Dr. Tsui’s lab skills include molecular biology, protein expression, and protein characterization for structural studies. In 2020, he joined the lab of Dr. Juan Du as a postdoctoral fellow to continue his research.


Current research focus

Using cryo-EM and electrophysiology to study membrane proteins

Education & Training

Postdoctoral scholar, University of California, San Francisco

Ph.D. in molecular biophysics, Florida State University  
Thesis: Characterization of a novel CRISPR Type II-C Cas9 endonuclease from bacterial thermophile Acidothermus Cellulolyticus 11B

B.S. in chemistry, University of California, San Diego

Awards & External Funding

CCSF-UCSF Inclusive Mentoring Fellow (2020)

Pending U.S. patent application no. US20180265864A1 (2019)

Kasha Award, Institute of Molecular Biophysics, Florida State University (2018)

American Heart Association Predoctoral Fellowship (Great Southeast Affiliates) (2015–2017)

FSU Fellows Society, Florida State University (2015)

JINS (Joint Institute for Neutron Sciences) Travel Award for 4th Workshop on Neutron Scattering Application in Structural Biology, Oak Ridge National Lab (June 2013)

FSU Dean’s Scholarship, Florida State University (2012–2013)

The Bruce Hass Memorial Award, Santa Monica College (2008)


To view a list of selected publications click below.

Read More

Tsui TKM, Hand TH, Duboy ED, Li H. 2017. The impact of DNA topology and guide length on target selection by a cytosine-specific Cas9. ACS Synthetic Biol  6(6):1103–1113.

Tsui TKM, Li H. 2015. Structure principles of CRISPR-Cas surveillance and effector complexes. Annual Rev Biophys 44:229–255.