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May 2021

Olivia S. Rissland, Ph.D. – VAI Seminar Series

May 26 @ 12:00 pm

Control of RNA Binding Proteins During Early Embryogenesis The maternal-to-zygotic transition (MZT) is a conserved step in animal development, where control is passed from the maternal to the zygotic genome. Although the MZT is typically considered from its impact on the transcriptome, we previously found that three maternally deposited Drosophila RNA binding proteins (ME31B, Trailer Hitch , and Cup) are also cleared during the MZT by unknown mechanisms. Here, we show that these proteins are degraded by the ubiquitin-proteasome system.…

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June 2021

Warren Hirst, Ph.D. – VAI Seminar Series

June 2 @ 12:00 pm

Developing novel Parkinson’s disease therapeutics: Opportunities and challenges Warren Hirst is Senior Director and head of the movement disorders preclinical research efforts in Biogen’s Research organization, a role he has led since joining them in 2016. Warren is responsible for developing and driving a diverse preclinical portfolio of programs, using multiple modalities, from antibodies and antisense oligonucleotides, in collaboration in Ionis, to gene therapy and small molecules, targeting mechanisms strongly supported by human genetics and pathology, to deliver novel disease-modifying…

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Thomas Montine, M.D., Ph.D. – Jay Van Andel Seminar Series

June 30 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States

“Synaptopathology in Alzheimer’s and Parkinson’s diseases” Dr. Montine received his education at Columbia University (BA in Chemistry), the University of Rochester (PhD in Pharmacology), and McGill University (MD and CM). His postgraduate medical training was at Duke University, and he was junior faculty at Vanderbilt University where he was awarded the Thorne Professorship in Pathology. In 2002, Dr. Montine was appointed as the Alvord Endowed Professor in Neuropathology and Director of the Division of Neuropathology at the University of Washington.…

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July 2021

Origins of Cancer

July 22 - July 23
Virtual MI United States

Origins of Cancer is a scientific symposium that brings together students, scientists and medical professionals to discuss the latest breakthroughs in cancer research. The 2021 meeting will delve into the emerging field of cancer neuroscience. Speakers will discuss the unique genetics and epigenetics of brain tumors, neural signaling mechanisms that influence tumor initiation and progression, the cellular pathways driving epidemiologic links between cancer and neurodegenerative disease, the neurotoxicity of cancer treatments and more.

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August 2021

Shane Liddelow, Ph.D. – Jay Van Andel Seminar Series

August 18 @ 12:00 pm

Title TBD Speaker Information Shane Liddelow, Ph.D. New York University– Langone Time & Location 12:00 pm on Zoom VAI Host: Patrik Brundin, M.D., Ph.D. Questions? For questions, please contact Kim Cousineau at 616.234.5684.

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Pablo Sardi, Ph.D. – VAI Seminar Series

August 25 @ 12:00 pm

Lysosomal dysfunction in Parkinson's disease: from genetics to the clinic Dr. Pablo Sardi is the Global Head of Rare and Neurologic Diseases Therapeutic Area and a Scientific Fellow at Sanofi. In this capacity, Pablo leads several teams of scientists working with a variety of therapeutic modalities to discover and develop transformative medicines for patients with rare and neurologic diseases (including rare metabolic, lysosomal, renal, hematologic, skeletal, and muscular diseases; as well as neurologic diseases comprising multiple sclerosis, ALS/FTD, Parkinson’s disease,…

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September 2021

Greg Wang, Ph.D. – VAI Seminar Series

September 22 @ 12:00 pm
Virtual MI United States

The language of chromatin modifications in human cancers Dr. Greg Wang is currently Associate Professor at UNC Lineberger Comprehensive Cancer Center & Dept of Biochemistry and Biophysics, University of North Carolina (UNC) at Chapel Hill, NC, USA. He received the PHD degree from University of California, San Diego, followed by a postdoctoral training at Rockefeller University. Dr. Wang’s research programs focus on mechanistic understanding of how chemical modifications of chromatin (including methylations of DNA and histone tails) regulate gene expression…

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Joseph Nadeau, Ph.D. – VAI Seminar Series

September 29 @ 12:00 pm
Virtual MI United States

Nature, nurture and the third dimension of phenotypic variation and disease risk JHN is an internationally-recognized expert in genetic, genomic, developmental, metabolic, bioinformatic, computational and systems studies of mouse models of human disease as well as translation of results to studies in humans. JHN has been a pioneer in comparative genomics (comparative gene mapping), genetics and systems studies of mouse models of human disease (chromosome substitution strains), and transgenerational effects on cancer, metabolism, embryogenesis, reproduction and behavior (epigenetic inheritance), His…

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October 2021

Grand Challenges in Parkinson’s Disease

October 6 - October 8
Virtual MI United States

Grand Challenges in Parkinson’s Disease brings together hundreds of scientists, clinicians and people with Parkinson’s to explore the latest Parkinson’s disease research. The 2021 symposium will focus on the influence of genetic risk factors on cell and brain biology, including risk for Parkinson’s and the roles of organellar trafficking, lipid metabolism, the endolysosomal system and neuropathology. Speakers also will discuss how genetic factors may be leveraged for treatment with a special focus on clinical trials, drug discovery and biomarker development that…

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Postdoc Preview

October 14 - October 16
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States

Are you a senior graduate student exploring your postdoc options? VAI Postdoc Preview is a three-day program that provides selected applicants the opportunity to visit Van Andel Institute to learn about our postdoctoral training opportunities, meet one-on-one with our internationally recognized faculty and explore our extensive scientific resources, including our state-of-the-art Core Technologies and Services. This year’s Preview will be held Thursday, Oct. 14 through Saturday, Oct. 16. The application period is now closed. There is no cost to attend.…

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