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October 2018

Cun-Yu Wang, D.D.S., Ph.D. – VARI Seminar Series

October 17, 2018 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Title TBD Speaker Information Cun-Yu Wang, D.D.S., Ph.D. University of California, Los Angeles Time & Location 12:00 pm at Van Andel Institute Conference Room 3104/3105 VARI Host: Tao Yang, Ph.D. Questions? For questions, please contact Kim Cousineau at 616.234.5684.

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November 2018

Eva Nogales, Ph.D. – VARI Seminar Series

November 14, 2018 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Title TBD Speaker Information Eva Nogales, Ph.D. University of California, Berkeley Time & Location 12:00 pm at Van Andel Institute Conference Room 3104/3105 VARI Host: Huilin Li, Ph.D. Questions? For questions, please contact Kim Cousineau at 616.234.5684.

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Jean-Pierre Issa, M.D. – VARI Seminar Series

November 28, 2018 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Title TBD Speaker Information Jean-Pierre Issa, M.D. Temple University Time & Location 12:00 pm at Van Andel Institute Conference Room 3104/3105 VARI Host: Postdoctoral Association Questions? For questions, please contact Kim Cousineau at 616.234.5684.

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March 2019

Robert Roeder, Ph.D. – VARI Seminar Series

March 13, 2019 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Mechanisms of transcriptional regulation through diverse co-activators Transcriptional regulation by gene- and cell-specific DNA-binding factors underlies key events in development, cell differentiation and transformation. However, their effects on specific genes depend upon complex arrays of cofactors that include both chromatin modifying factors (e.g., histone acetyl-transferases and methyl-transferases) and other factors (e.g., Mediator and TAFs) that facilitate more direct communication between enhancer-bound regulatory factors and the general transcription machinery. Emphasizing biochemical studies with cell-free systems reconstituted with recombinant chromatin templates and…

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April 2019

David Gilbert, Ph.D. – VARI Seminar Series

April 17, 2019 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Regulation of replication timing and chromosome architecture Our goal is to understand how mammalian chromosomes are organized within the nucleus to carry out their functions. DNA replication provides an excellent forum in which to study chromosome structure and function. Structural and functional units of chromosomes replicate coordinately, often through the synchronous firing of clusters of replication origins that encompass domains of approximately 0.5 Mb. Each of these replication domains is programmed to replicate at a specific time during S-phase. In…

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May 2019

Brad Merrill, Ph.D. – VARI Seminar Series

May 1, 2019 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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THIS EVENT HAS BEEN CANCELLED.  Novel mechanisms controlling pluripotency of stem cells identified by genome editing approaches The early mammalian embryo traverses remarkably different environments before specification of somatic cell lineages occurs during gastrulation. Transitioning through different states of pluripotency is thought to provide cells a method of accommodating different conditions while they expand in numbers during the embryo’s journey. I will present some of our efforts to elucidate the mechanisms stem cells use to transition between states of pluripotency.…

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Bryan G. Allen, M.D., Ph.D. – VARI Seminar Series

May 15, 2019 @ 12:00 pm - 1:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Manipulating metabolic oxidative stress to enhance cancer therapy Dr. Allen is an assistant professor and physician-scientist in the Department of Radiation Oncology at the University of Iowa. Dr. Allen is a redox biochemist with expertise in manipulating metabolic oxidative stress to enhance radiation and chemotherapy effectiveness and reduce associated treatment related toxicities. He is also a practicing radiation oncologist who participates in developing and running investigator initiated clinical trials. Speaker Information Bryan G. Allen, M.D., Ph.D. Tenure-Track Assistant Professor Department…

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June 2019

Margaret Goodell, Ph.D. – VARI Seminar Series

June 12, 2019 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Title TBD Speaker Information Margaret Goodell, Ph.D. Professor and Director, Stem Cells and Regenerative Medicine Center Vivian L. Smith Chair in Regenerative Medicine Co-Leader, Cancer Cell and Gene Therapy Baylor College of Medicine Time & Location 12:00 pm at Van Andel Institute Conference Room 3104/3105 VARI Host: Peter A. Jones, Ph.D., D.Sc. (hon) Questions? For questions, please contact Kim Cousineau at 616.234.5684.

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David Sulzer, Ph.D. – VARI Seminar Series

June 19, 2019 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Multiple interactions between dopamine and alpha-synuclein Alpha-synuclein plays an important physiological function by inhibiting the exocytosis of synaptic vesicles but is also plays an instrumental role in the cause of Parkinson’s and additional diseases. We will discuss evidence suggesting how intracellular changes in the handling of this protein may initiate this disease and how it may lead to neuronal death including through steps in the acquired immune system. Speaker Information David Sulzer, Ph.D. Professor Departments of Psychiatry, Neurology, and Pharmacology…

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September 2019

Da-Neng Wang, Ph.D. – VAI Seminar Series

September 25, 2019 @ 12:00 pm
Van Andel Institute, 333 Bostwick Ave. NE
Grand Rapids, MI 49503 United States
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Title TBD Speaker Information Da-Neng Wang, Ph.D. Professor, Department of Cell Biology NYU Medical School Time & Location 12:00 pm at Van Andel Institute Conference Room 3104/3105 VARI Host: Huilin Li, Ph.D. Questions? For questions, please contact Kim Cousineau at 616.234.5684.

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